Trimethoprim-sulphamethoxazole (Septrin) in the treatment of rectal gonorrhoea.

Trimethoprim-sulphamethoxazole (Septrin) in the treatment of rectal gonorrhoea.

The recent increase in some parts of London of syphilis acquired homosexually (Lancet, 1964; Brit. med. J7., 1967) has indicated that a drug of nontreponemicidal properties is to be preferred in the treatment of gonococcal proctitis in homosexual men. Septrin was considered as a potentially useful remedy in these circumstances. Though taken orally and so subject to error or misuse, it needs be ...

Sulphamethoxazole-trimethoprim in the treatment of gonorrhoea.

SELECTION OF PATIENTS All patients who attended the Plymouth clinic during that period and from whom smears and cultures yielded gonococci were included in the trial with the following exceptions: (i) Pregnant women (ii) Known prostitutes (iii) Men with gonococcal proctitis (iv) Patients who had defaulted on previous occasions (v) Patients who would be unable to attend for regular follow-up. A ...

Treatment of gonorrhoea with trimethoprim-sulphamethoxazole in Uganda.

Penicillin is still satisfactory as the main treatment for gonorrhoea in Uganda, but there is evidence that its usefulness is declining. In 1961, there was a treatment failure rate of only 4 per cent. with a single dose of 0-3 mega units penicillin aluminium mono-stearate (PAM) (Kibukamusoke, 1965); four times that dose-1V2 mega units-gave a failure' rate of 17-9 per cent. in 1966 (Arya, unpubl...

Treatment of chancroid. A comparison of sulphamethoxazole and trimethoprim-sulphamethoxazole.

Since sulphonamides are no longer predictably effective in the treatment of chancroid the combination of trimethoprim-sulphamethoxazole (TMP-SMX) was evaluated to identify other effective regimens. One hundred and nine patients with genital ulcers (75 men and 34 women) seen at the Special Treatment Clinic in Nairobi, Kenya, were randomly assigned to treatment with a seven day course of either s...

Treatment of gonorrhoea with trimethoprim-sulphamethoxazole and probenecid plus procaine penicillin in Rwanda.